The Bump Array
The bump array is a microfluidic particle-separation device that utilizes asymmetric bifurcation of laminar flow around obstacles. Much faster than conventional pulsed field gel electrophoresis, the bump array (like the DNA prism) is capable of separating large DNA in 10 minutes with 12% resolution. Larger particles are displaced as they move through the matrix while smaller particles remain in the streamlines. Future directions include separating chromosomal DNA, increasing resolution, and separating shorter DNA fragments by scaling down post and gap sizes. The following image is from the paper below.
